4-HO-MET Powder

Every research project begins with the same challenge: finding reliable, pure chemical compounds that meet high scientific standards. For researchers working with tryptamine derivatives, this search is essential. 4-HO-MET powder is an important component in this field of study—a synthetic tryptamine that requires precision and quality for reliable laboratory results.

Too often, research projects are hindered by suppliers who provide incomplete specifications, inconsistent purity levels, or lack essential documentation. This slows scientific progress and can undermine the reliability of research data. When molecular structures and chemical properties are not accurately characterized, months of work can become worthless.

That is why ordering 4-HO-MET from a specialized supplier is not a luxury, but a necessity. ABC Party Netherlands aims to serve as a reliable partner for research institutions and laboratories that refuse to compromise on chemical raw materials.

Molecular Characteristics and Chemical Properties

4-Hydroxy-N-methyl-N-ethyltryptamine belongs to the substituted tryptamine class and shares structural similarities with naturally occurring compounds such as psilocin. Its molecular formula is C₁₃H₁₈N₂O, with a molecular weight of 218.29 g/mol.

The compound is typically supplied as a white to beige powder in salt form (hydrochloride or fumarate). Its indole-core structure, characteristic of serotonergic compounds, makes it of interest for neurochemical research and receptor-binding studies.

Key Structural Features

• Substituted indole core system
• Hydroxyl group at position 4 of the indole ring
• N-methyl-N-ethyl substituents on the terminal amine
• Stable crystalline structure in salt form

Technical Specifications

• Chemical Name: 4-Hydroxy-N-methyl-N-ethyltryptamine
• Molecular Formula: C₁₃H₁₈N₂O
• Molecular Weight: 218.29 g/mol
• CAS Number: 77872-41-4
• Physical Form: White/beige crystalline powder
• Purity: ≥98% (HPLC)
• Solubility: Soluble in ethanol and methanol
• Storage Temperature: 2–8°C, dry and dark conditions
• Stability: Stable under recommended conditions

Analytical Verification

Each batch of 4-HO-MET powder undergoes extensive analytical verification using high-performance liquid chromatography (HPLC) to ensure molecular purity. Nuclear magnetic resonance (NMR) spectroscopy confirms structural integrity, while mass spectrometry provides definitive molecular identification.

This multi-analytical approach is intended to reduce uncertainty often associated with lower-quality research chemicals.

Research Applications

Receptor-Binding Studies

In vitro research indicates that 4-HO-MET primarily acts as an agonist at serotonin 5-HT₂A receptors, making it useful for:

• Neuroreceptor mapping studies
• Signal cascade research
• Structure–activity relationship studies
• Pharmacodynamic profiling

Analytical Method Development

Researchers may use 4-HO-MET for:

• Calibration of detection systems
• Development of separation techniques
• Validation of spectroscopic methods
• Training of analytical personnel

Laboratory Handling and Storage

Safety Measures

Recommended laboratory precautions include:

• Chemical-resistant gloves (nitrile or neoprene)
• Safety goggles with side protection
• Laboratory coat
• Adequate ventilation or use of a fume hood

Storage Requirements

• Temperature: 2–8°C
• Humidity: <10% relative humidity
• Light protection: amber or opaque containers
• Inert atmosphere (nitrogen or argon) for long-term storage

Stability and Degradation

Under optimal conditions, 4-HO-MET is reported to remain stable for more than 24 months. Potential degradation pathways include:

• Oxidation of the hydroxyl group
• Hydrolysis in humid conditions
• Photodegradation from UV exposure
• Thermal decomposition above 40°C

Quality Assurance and Documentation

Each package includes:

• Certificate of Analysis (CoA)
• Material Safety Data Sheet (MSDS)
• Purity certification
• Storage recommendations

Important Notice

All products are intended solely for research purposes and are not intended for human consumption.